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侯卓成

侯卓夫编农成,    中国农业大学动物科学技术学院教授,博士。

  • 中文名称 侯卓成
  • 毕业院校 中国农业大学
  • 职业 教师
  • 主要成就 在家禽基因组学、分子育种、新品种培育等取得一些进展,先后解析了鸡矮小致死性状遗传机理、北京鸭、绿头野鸭、蛋鸭高质量基因组并被作为国际鸭参考基因组;构建了鹌鹑参考基因组并解析了鹌鹑早熟遗传机理等
  • 职称 国家水禽产业技术体系岗位科学家、全国水禽遗传改良计划专家组成员、中国畜牧兽医学会信息技术分会常务理事、农业农村部动物遗传育种与繁殖重点实验室(家畜)学科群主任助理等。

履历

  学习与工作经历:

  2002.7-现在中国来自农业大学动物科技学院

  2007.10-2010.12PRB/NICHDResearchAssistant

  2004.9-2007.6中国农业大学动物遗传育种与繁殖多验测冲笑专业博士

  2002.7-2002.8中国科学360百科院昆明动物研究所国家自然基金委分子群体遗传与进化暑期学

  2000.7-2000.8厦门大学国家自然基金委第一届生物信息学暑期学校

  1999.9-过川样呼获吸脸列味每2002.6中国农业大学动物遗传育种与繁殖专业硕士

  1995.9-1999.6载联意积之夫厚于把物中国农业大学动物遗传育种与繁殖专业本科

兼职

  中国畜牧兽医学会信息技术分会常务理事、全国水禽遗传改良计划专家组成员

研究方向

  (1)家禽繁殖功能基因组学与生物信息学

  (2)家禽分子育种

主要论著

究而调待请亚永久等  1. Yin Z, Lian L, 振派材范重区测裂每良Zhu F, Zhang ZH, 来自Hincke M, Yang N, Hou ZC: The transcriptome landscapes of ovary and three oviduct segments during chicken (Gallus gallus) egg formation. GENOMICS 2020, 112(1):243-251.

  2. Zhu 宪该菜独呀成与F, Cui QQ, Yang YZ, Hao JP, Yang FX, Hou ZC: Genome-wide association study of the level of blood components in Pekin ducks. GENOMICS 2020, 112(1):379-387.

  3. Chen X, Li X, He Z, Hou Z械会片汉节校转易者持说, Xu G, Yang N, Zheng J: Comparative study of eg控精群座施示守液gshell antibacterial effectivity in precocial and altric360百科ial birds using E王发搞方知定哥蒸胞功scherichia coli. 山露举危品知身适情帝PLOS ONE 2019, 14(7):e220054.

  4. Deng MT, Zhu F, Yang YZ, Yang FX, Hao JP, Chen S祖击少染R, Hou ZC: Genome-wide association study reveals novel loci associated with body size and carcass yields in Pekin ducks. BMC GENOMICS 2019, 20(1):1.

  5. Ding S, Li G, Chen S, Zhu F, Hao J, Yang F, Hou Z: Comparison of carcass and meat quality traits b轴植etween lea者有n and fat Pekin ducks. Asian-Australas J Anim Sci 2019.

  6. Wang Z, Yin ZT, Zhang F, Li XQ, Chen SR, Yang N, Porter T止的倍她天E, Hou Z: Dynamics of transcriptome changes during subcutaneous preadipocyte differentiation in ducks. BMC GENOMICS 2019, 20(1):688.

  7. Xing K, Zhao X, Ao H, 养非还京片钢拉Chen S, Yang T, T战杨国末看非an Z, Wang Y, Zhang F, Liu Y, Ni H et al: Tr缺夜针anscriptome analysis of miRNA and mR低形升十约斤例三界军领NA in the livers of pigs with highly diverged backfat thickness. Sci Rep 2019, 9(1):16740.

  8. Yan W, Sun C, Zheng J, Wen C, Ji C, Zhang D, Chen Y, Hou Z, Yang 室烧执只期触喜N: Efficacy of Fecal Sampling a只帝卫官重准吗报滑甲标s a Gut Proxy in 第径钱吸料盟第长座均the Study of Chicken Gut Microbiota. FRONT MICROBIOL 2019, 10:2126.

  9. Yin ZT, Zhu F, Lin FB, Jia T, Wang Z, Sun DT, Li GS, Zhang CL, Smith J, Yang N et al: Revisiting avian 'missing' genes from de novo assembled transcripts. BMC GENOMICS 2019, 20(1):4.

  10. Yin Z, Zhang F, Smith J, Kuo R, Hou ZC: Full-length transcriptome sequencing from multiple tissues of duck, Anas platyrhynchos. SCI DATA 2019, 6(1):275.

  11. Zhu F, Cheng SR, Yang YZ, Hao JP, Yang FX, Hou ZC: Genome-Wide Association Study of Growth and Feeding Traits in Pekin Ducks. FRONT GENET 2019, 10:702.

  12. Zhu F, Zhang F, Hincke M, Yin ZT, Chen SR, Yang N, Hou ZC: iTRAQ-Based Quantitative Proteomic Analysis of Duck Eggshell During Biomineralization. PROTEOMICS 2019, 19(11):e1900011.

  13. Hou Z, An L, Han J, Yuan Y, Chen D, Tian J: Revolutionize livestock breeding in the future: an animal embryo-stem cell breeding system in a dish. J Anim Sci Biotechnol 2018, 9:90.

  14. Lin FB, Zhu F, Hao JP, Yang FX, Hou ZC: In vivo prediction of the carcass fatness using live body measurements in Pekin ducks. Poult Sci 2018, 97(7):2365-2371.

  15. Wu Y, Zhang Y, Hou Z, Fan G, Pi J, Sun S, Chen J, Liu H, Du X, Shen J et al: Population genomic data reveal genes related to important traits of quail. GIGASCIENCE 2018, 7(5).

  16. Xie S, Yang X, Wang D, Zhu F, Yang N, Hou Z, Ning Z: Thyroid transcriptome analysis reveals different adaptive responses to cold environmental conditions between two chicken breeds. PLOS ONE 2018, 13(1):e191096.

  17. Liu L, Fan Y, Zhang Z, Yang C, Geng T, Gong D, Hou Z, Ning Z: Analysis of gene expression and regulation implicates C2H9orf152 has an important role in calcium metabolism and chicken reproduction. ANIM REPROD SCI 2017, 176:1-10.

  18. Shi S, Shen Y, Zhang S, Zhao Z, Hou Z, Zhou H, Zou J, Guo Y: Combinatory Evaluation of Transcriptome and Metabolome Profiles of Low Temperature-induced Resistant Ascites Syndrome in Broiler Chickens. Sci Rep 2017, 7(1):2389.

  19. Shi S, Shen Y, Zhang S, Zhao Z, Hou Z, Zhou H, Zou J, Guo Y: Combinatory Evaluation of Transcriptome and Metabolome Profiles of Low Temperature-induced Resistant Ascites Syndrome in Broiler Chickens. Sci Rep 2017, 7(1):2389.

  20. Weckle A, McGowen MR, Xing J, Chen C, Sterner KN, Hou ZC, Romero R, Wildman DE: Ancestral resurrection of anthropoid estrogen receptor beta demonstrates functional consequences of positive selection. MOL PHYLOGENET EVOL 2017, 117:2-9.

  21. Zhu F, Gao Y, Lin F, Hao J, Yang F, Hou Z: Systematic analysis of feeding behaviors and their effects on feed efficiency in Pekin ducks. J Anim Sci Biotechnol 2017, 8:81.

  22. Jin S, Zhu F, Wang Y, Yi G, Li J, Lian L, Zheng J, Xu G, Jiao R, Gong Y et al: Deletion of Indian hedgehog gene causes dominant semi-lethal Creeper trait in chicken. Sci Rep 2016, 6:30172.

  23. Lipovich L, Hou ZC, Jia H, Sinkler C, McGowen M, Sterner KN, Weckle A, Sugalski AB, Pipes L, Gatti DL et al: High-throughput RNA sequencing reveals structural differences of orthologous brain-expressed genes between western lowland gorillas and humans. J COMP NEUROL 2016, 524(2):288-308.

  24. Tan K, An L, Miao K, Ren L, Hou Z, Tao L, Zhang Z, Wang X, Xia W, Liu J et al: Impaired imprinted X chromosome inactivation is responsible for the skewed sex ratio following in vitro fertilization. Proc Natl Acad Sci U S A 2016, 113(12):3197-3202.

  25. Xing K, Zhu F, Zhai L, Chen S, Tan Z, Sun Y, Hou Z, Wang C: Identification of genes for controlling swine adipose deposition by integrating transcriptome, whole-genome resequencing, and quantitative trait loci data. Sci Rep 2016, 6:23219.

  26. Xing K, Zhu F, Zhai L, Liu H, Wang Y, Wang Z, Chen S, Hou Z, Wang C: Integration of transcriptome and whole genomic resequencing data to identify key genes affecting swine fat deposition. PLOS ONE 2015, 10(4):e122396.

  27. Zhao H, Sui L, Miao K, An L, Wang D, Hou Z, Wang R, Guo M, Wang Z, Xu J et al: Comparative analysis between endometrial proteomes of pregnant and non-pregnant ewes during the peri-implantation period. J Anim Sci Biotechnol 2015, 6(1):18.

  28. Zhu F, Yuan JM, Zhang ZH, Hao JP, Yang YZ, Hu SQ, Yang FX, Qu LJ, Hou ZC: De novo transcriptome assembly and identification of genes associated with feed conversion ratio and breast muscle yield in domestic ducks. ANIM GENET 2015, 46(6):636-645.

  29. Li G, Li D, Yang N, Qu L, Hou Z, Zheng J, Xu G, Chen S: A genome-wide association study identifies novel single nucleotide polymorphisms associated with dermal shank pigmentation in chickens. Poult Sci 2014, 93(12):2983-2987.

  30. Shi S, Shen Y, Zhao Z, Hou Z, Yang Y, Zhou H, Zou J, Guo Y: Integrative analysis of transcriptomic and metabolomic profiling of ascites syndrome in broiler chickens induced by low temperature. MOL BIOSYST 2014, 10(11):2984-2993.

  31. Sipahi L, Uddin M, Hou ZC, Aiello AE, Koenen KC, Galea S, Wildman DE: Ancient evolutionary origins of epigenetic regulation associated with posttraumatic stress disorder. FRONT HUM NEUROSCI 2014, 8:284.

  32. Sui L, An L, Tan K, Wang Z, Wang S, Miao K, Ren L, Tao L, He S, Yu Y et al: Dynamic proteomic profiles of in vivo- and in vitro-produced mouse postimplantation extraembryonic tissues and placentas. BIOL REPROD 2014, 91(6):155.

  33. Xing K, Zhu F, Zhai L, Liu H, Wang Z, Hou Z, Wang C: The liver transcriptome of two full-sibling Songliao black pigs with extreme differences in backfat thickness. J Anim Sci Biotechnol 2014, 5(1):32.

  34. Zhang Q, Liu L, Zhu F, Ning Z, Hincke MT, Yang N, Hou Z: Integrating de novo transcriptome assembly and cloning to obtain chicken Ovocleidin-17 full-length cDNA. PLOS ONE 2014, 9(3):e93452.

  35. Fan YF, Hou ZC, Yi GQ, Xu GY, Yang N: The sodium channel gene family is specifically expressed in hen uterus and associated with eggshell quality traits. BMC GENET 2013, 14:90.

  36. Jie H, Lian L, Qu LJ, Zheng JX, Hou ZC, Xu GY, Song JZ, Yang N: Differential expression of Toll-like receptor genes in lymphoid tissues between Marek's disease virus-infected and noninfected chickens. Poult Sci 2013, 92(3):645-654.

  37. Nie J, An L, Miao K, Hou Z, Yu Y, Tan K, Sui L, He S, Liu Q, Lei X et al: Comparative analysis of dynamic proteomic profiles between in vivo and in vitro produced mouse embryos during postimplantation period. J PROTEOME RES 2013, 12(9):3843-3856.

  38. Wang Y, Wang C, Hou Z, Miao K, Zhao H, Wang R, Guo M, Wu Z, Tian J, An L: Comparative analysis of proteomic profiles between endometrial caruncular and intercaruncular areas in ewes during the peri-implantation period. J Anim Sci Biotechnol 2013, 4(1):39.

  39. Yuan J, Wang B, Huang Z, Fan Y, Huang C, Hou Z: Comparisons of egg quality traits, egg weight loss and hatchability between striped and normal duck eggs. Br Poult Sci 2013, 54(2):265-269.

  40. Hou ZC, Sterner KN, Romero R, Than NG, Gonzalez JM, Weckle A, Xing J, Benirschke K, Goodman M, Wildman DE: Elephant transcriptome provides insights into the evolution of eutherian placentation. GENOME BIOL EVOL 2012, 4(5):713-725.

  41. Hou ZC, Yang FX, Qu LJ, Zheng JX, Brun JM, Basso B, Pitel F, Yang N, Xu GY: Genetic structure of Eurasian and North American mallard ducks based on mtDNA data. ANIM GENET 2012, 43(3):352-355.

  42. Lu Y, Chen SR, Liu WB, Hou ZC, Xu GY, Yang N: Polymorphisms in Wnt signaling pathway genes are significantly associated with chicken carcass traits. Poult Sci 2012, 91(6):1299-1307.

  43. Jameson NM, Hou ZC, Sterner KN, Weckle A, Goodman M, Steiper ME, Wildman DE: Genomic data reject the hypothesis of a prosimian primate clade. J HUM EVOL 2011, 61(3):295-305.

  44. Wildman DE, Uddin M, Romero R, Gonzalez JM, Than NG, Murphy J, Hou ZC, Fritz J: Spontaneous abortion and preterm labor and delivery in nonhuman primates: evidence from a captive colony of chimpanzees (Pan troglodytes). PLOS ONE 2011, 6(9):e24509.

  45. Zhang Y, Hou ZC, Chen ZX, Zheng JX, Chen SR, Qu LJ, Li JY, Xu GY, Yang N: Low-density lipoprotein receptor-related protein 2 gene is associated with egg-quality traits in dwarf layers. Poult Sci 2011, 90(12):2718-2722.

  46. Goodman M, Sterner KN, Islam M, Uddin M, Sherwood CC, Hof PR, Hou ZC, Lipovich L, Jia H, Grossman LI et al: Phylogenomic analyses reveal convergent patterns of adaptive evolution in elephant and human ancestries. Proc Natl Acad Sci U S A 2009, 106(49):20824-20829.

  47. Hou ZC, Romero R, Wildman DE: Phylogeny of the Ferungulata (Mammalia: Laurasiatheria) as determined from phylogenomic data. MOL PHYLOGENET EVOL 2009, 52(3):660-664.

  48. Hou ZC, Yang N, Li JY, Xu GY: [Egg quality prediction by using Fourier transform near infrared reflectance spectroscopy (FT-NIR)]. Guang Pu Xue Yu Guang Pu Fen Xi 2009, 29(8):2063-2066.

  49. Hou Z, Romero R, Uddin M, Than NG, Wildman DE: Adaptive history of single copy genes highly expressed in the term human placenta. GENOMICS 2009, 93(1):33-41.

  50. Qu L, Liu W, Yang F, Hou Z, Zheng J, Xu G, Yang N: Origin and domestication history of Peking ducks deltermined through microsatellite and mitochondrial marker analysis. Sci China C Life Sci 2009, 52(11):1030-1035.

  51. Than NG, Romero R, Goodman M, Weckle A, Xing J, Dong Z, Xu Y, Tarquini F, Szilagyi A, Gal P et al: A primate subfamily of galectins expressed at the maternal-fetal interface that promote immune cell death. Proc Natl Acad Sci U S A 2009, 106(24):9731-9736.

  52. Than NG, Romero R, Erez O, Weckle A, Tarca AL, Hotra J, Abbas A, Han YM, Kim SS, Kusanovic JP et al: Emergence of hormonal and redox regulation of galectin-1 in placental mammals: implication in maternal-fetal immune tolerance. Proc Natl Acad Sci U S A 2008, 105(41):15819-15824.

  53. Hou ZC, Xu GY, Su Z, Yang N: Purifying selection and positive selection on the myxovirus resistance gene in mammals and chickens. GENE 2007, 396(1):188-195.

  54. Li XY, Qu LJ, Hou ZC, Yao JF, Xu GY, Yang N: Genomic structure and diversity of the chicken Mx gene. Poult Sci 2007, 86(4):786-789.

  55. Qu L, Li X, Xu G, Chen K, Yang H, Zhang L, Wu G, Hou Z, Xu G, Yang N: Evaluation of genetic diversity in Chinese indigenous chicken breeds using microsatellite markers. Sci China C Life Sci 2006, 49(4):332-341.

  56. Zhan K, Hou ZC, Li HF, Xu GY, Zhao R, Yang N: Molecular cloning and expression of the duplicated thyroid hormone responsive spot 14 (THRSP) genes in ducks. Poult Sci 2006, 85(10):1746-1754.

  57. Zhang LC, Ning ZH, Xu GY, Hou ZC, Yang N: Heritabilities and genetic and phenotypic correlations of egg quality traits in brown-egg dwarf layers. Poult Sci 2005, 84(8):1209-1213.

  58. Hou ZC, Yang N: Factors affecting codon usage in Yersinia pestis. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 2003, 35(6):580-586.

  59. Hou ZC, Yang N: [Advances in major histocompatibility complex research in poultry]. Yi Chuan 2002, 24(1):72-76.

  60. Hou ZC, Yang N: [Analysis of factors shaping S. pneumoniae codon usage]. Yi Chuan Xue Bao 2002, 29(8):747-752.

  中文核心期刊:

  [1]侯卓成.水禽育种技术以及自主化品种培育研究进展[J].养禽与禽病防治,2019(06):32-35.

  [2]杨宇泽,侯卓成,常卓,张权.北京鸭群体遗传多样性及遗传资源分析[J].中国畜牧杂志,2019,55(05):35-40.

  [3]林芳斌,崔倩倩,袁建敏,侯卓成.不同能蛋水平免填饲料对北京鸭皮脂性能的影响及性状相关分析[J].中国家禽,2016,38(14):22-26.

  [4]朱峰,王炎耘,郝金平,张金奉,杨宇泽,杨方喜,陈瑶,胡胜强,侯卓成.北京鸭骨质量性状和屠体性状的相关性研究[J].中国畜牧杂志,2015,51(23):1-5.

  [5]王炎耘,郝金平,李国程,袁建敏,杨方喜,陈瑶,胡胜强,侯卓成.日粮中添加不同比例纤维素对北京鸭生产性能的影响[J].中国家禽,2015,37(22):35-37.

  [6]朱峰,王炎云,郝金平,杨宇泽,李国臣,杨方喜,陈瑶,胡胜强,侯卓成.超声波法测量北京鸭皮脂性状及其与屠宰性状的相关分析[J].中国家禽,2015,37(16):6-9.

  [7]侯卓成. 我国水禽育种研究综述[N]. 中国畜牧兽医报,2014-11-16(012).

  [8]侯卓成. 养殖模式决定水禽育种方向[N]. 中国畜牧兽医报,2014-11-16(012).

  [9]边蓓蕾,郝金平,杨方喜,胡胜强,侯卓成.北京鸭采食行为及其剩余采食量与部分经济性状的相关研究[J].中国家禽,2014,36(16):8-11.

  [10]任康,张权,肖炜,云鹏,宁中华,侯卓成.利用微卫星标记分析不同保种场的保种效果[J].黑龙江动物繁殖,2014,22(03):8-14.

  Internationalmeetingposters:

  (1)HouZhuocheng,RomeroR,UddinM,ThanNG,WildmanDE,AdaptiveevolutionofhighlyexpressedgeneinthehumanplacentafromEutheriadivergenceleadingtohuman,Evolution,

  Minneapolis,Minnesota,USA,2008

  (2)HouZhuocheng,XingJun,ChenCaoyi,RomeroRoberto,GoodmanMorris,WildmanDerekE.,Adaptiveevolutioninprimateestrogenreceptorsinhibittheabilityofhormonebinding,

  74thSymposium:Evolution-TheMolecularLandscape,ColdSpringHarborLaboratory,USA,2009

  Databases:

  ·HouZC,ZhouX,XuGY,SuZ,YangN,2007,Vertebratelineage-specificduplicategenedatabase(VLSD),( 略).

  Oralpresentations:

  ·HouZC.Naturalselectioninthechickengenome,2007,3rdInternationalconferenceonquantitativegenetics(ICQG),Hangzhou,China.

  ·HouZC.Identification,characteristicsandexpressionanalysisofbird-specificgenes,2012,33rdInternationalSocietyforAnimalGeneticsConference(ISAG),Cairns,Australia

获奖成果

  荣获北京科技进步一等奖,教育部科技进步二等奖,全国农牧渔业丰收一等奖,大北农青年学者奖等。

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