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王启鸣

王启鸣,男,郑州大学附属肿瘤医院、河南省肿瘤医院内科副来自主任,呼吸内科三病区主任拿封,主任医师 ,360百科肿瘤学博士,美国安德森癌症中心博士后,郑州大学硕士生导师,河南省学术技术带头人,河南省优秀中青年卫生科技创新人才,河南省肿瘤医院优秀拔尖人才 ,河南省医学会医疗事故(医疗损害)技术鉴定专家库成员。

  • 中文名称 王启鸣
  • 国籍 中国
  • 职业 郑州大学附属肿瘤医院/河南省肿瘤医院内科副主任
  • 性别 男

研究方向

  胸部肿瘤(食管癌、肺癌) 的发病机制和个体化治疗,肿瘤干细胞与化放疗耐药 。主攻难外陆愿术变展反大信治性肺癌和小细胞肺癌。

荣誉

  2021年10月,入选第十一批河南省优秀专家人选公示续做目放占议机刻田名单。

著作译作

  1某盐最言林服权夜及充.《肿瘤分子靶向治疗新进展》 ,2012年,科学出版社,副主编;

  2.《培沉测州维响比甲体整合miRNA肿瘤学基础》,2013年,科学出吸斤版社,副主编。

获奖情况

  1来自.性激素及其受体与食管癌变的关系;河南省卫生厅科技进步二等奖;(第红农限措管门商苦一完成人)

  2.晚期非小细胞肺癌靶向治疗优势人好通它群的筛选;河南省科技进步二等奖;(第三完成人)

出诊信息

  周三上午 ,周四下午

学术兼职

  《Cancer》、《AnnalsofOncology》、《Biochimie》、《CancerMedicine》、《APMIS》、《MedicalScienceMo360百科nitor》等SCI期刊审稿人 ;

  美国AA积米往修片搞使都伤需纸CR会员;

  河南省抗癌协会化疗专业委员会,委员;

  河南省抗癌协会肺癌专业委员会,委员住弱情喜销娘十;

  河南省抗癌协会头颈肿瘤专业委员会,委员;

  河南省抗癌协会肿瘤流行病与病因专业委员会,委员;

发表论文

 开选承争八强美价 1. Qi YJ, Ward DG, Pang C, Wang QM, Wei W, Ma J, Zhang J, Lou Q, Shimwell NJ, Martin A, Wong N, Chao WX, Wang M, Ma YF, Johnson PJ. Proteomic profiling of N-linked glycoproteins identifies ConA-binding procathepsin D as a novel serum biomarker for hepatocellular carcinoma. Proteomics. 2014 Feb;14(2-3):186-95. doi: 10.1002/pmic.20袁才球期1300226.

  2. Shen R, Liu H, Wen J, Liu Z, Wang LE, Wang Q, Tan D, Ajani JA, Wei Q. Genetic polymorphisms in the microRNA binding-sites of the thymidylate synthase gene predict risk and survival in gastric cancer. Mol Carcinog. 2014 Apr 23. doi: 10.1002/mc.22160. [Epub ahead of print]

  3. Wen J, Liu H, Wang Q, Liu Z, Li Y, Xiong H, Xu T, Li P, Wang LE, Gomez DR, Mohan R, Komaki R, Liao Z, Wei Q. Genetic variants of the LIN28B gene predict severe radiation pneu片绝川源半monitis in patients with non-small c最才变孩械影航水百ell lung cancer treated with definitive radiation therapy. Eur J Cancer. 2014 Apr 25. pii: S0959-80后让读策49(14)00251-2. doi: 10.额妈及查入吗置字东1016/j.ejca.2014.03.008. [Epub ahead of print]

  4. Wang Q, Liu H, Xiong H, Liu Z, Wang LE, Qian J, Muddasani R, Lu V, Tan D, Ajani JA, Wei Q. Polymorphism蛋临九约标s in the microRNA binding-site in the ste鲜列唱门脚打火创属另扬m cell marker gene CD133 modify susceptibility to and survival of gastric cancer. Mol Carcinog. 2013 Dec 2. doi: 10.1002/mc.22113. [Epub ahead of print]

  5. Xiong H, Liao Z, Liu Z, Xu T, Wang Q, Liu H, Komaki R, Gomez D, Wang LE, Wei Q. ATM Polymorphisms Predict Severe Radiation Pneumonitis in Patients With Non-Small Cell Lung Cancer Treated With Definitive Radiation Therapy. Int J Radiat Oncol Biol Phys. 2012 Nov 12. doi:pii: S0360-3016(12)03602-4. 10.1016/j.ijrobp.2012.09.024

  6. Qian J, Qu HQ, Yang L, Yin M, Wang Q, Gu S, Wu Q, Zhao X, Wu W, Wu J, Tan X, Chen W, Wang H, Wang J, Fan W, Chen H, Han B, Lu D, Wei Q, Jin L. Association Between CASP8 and CASP10 Polymorphisms and Toxicity Outcomes With Platinum-Based Chemotherapy in Chinese Patients With Non-Small Cell Lung Cancer. Oncologist. 2012;17(12):1551-61. doi: 10.1634/theoncologist.2011-0419. Epub 2012 Jul 27.

  7. Zhang T, Zhao D, Wang Q, Yu X, Cui Y, Guo L, Lu SH. MicroRNA-1322 Regulates ECRG2 Allele Specifically and acts as a potential Biomarker in Patients with Esophageal Squamous Cell Carcinoma. Mol Carcinog. 2012 Feb 7. doi: 10.1002/mc.21880. [Epub ahead of print]. (SCI,IF 3.265)

  8. Wang H, Zhang G, Li P, Yan X, Wang Q, Zhu H, Qi G, Fan Q, Ma Z. Differential efficacy of gefitinib across age groups in treatment of advanced lung adenocarcinoma. Pharmazie. 2012 Jan;67(1):80-5

  9. Zhang T, Wang Q, Zhao D, Cui Y, Cao B, Guo L, Lu SH.The oncogenetic role of microRNA-31 as a potential biomarker in oesophageal squamous cell carcinoma. Clin Sci (Lond). 2011, 121(10):437-47. (co-first author) (SCI,IF 4.613)

  10.Wang QM, Wang S, Wang HJ, Li P, Ma ZY. MicroRNAs: novel biomarkers for lung cancer diagnosis, prediction and treatment. Exp Biol Med (Maywood). 16 February 2012, 10.1258/ebm.2011.011192. (SCI,IF 3.0)

  11. Wang QM, Qi YJ, Jiang Q, Ma YF, Wang LD. Relevance of serum estradiol and estrogen receptor beta expression in high-incidence area for esophageal squamous cell carcinoma. Med Oncol. 2011; 28(1):188-93.(SCI,IF 2.210)

  12. Wang QM, Yuan L, Qi YJ, Ma ZY, Wang LD.Estrogen analogues: promising target for prevention and treatment of esophageal squamous cell carcinoma in high risk areas. Med Sci Monit. 2010; 16(7):HY19-22. (SCI,IF 1.699)

  13.Wang Q, Wang H, Li P, Zhu H, He C, Wei B, Ma J, Ma Z. Erlotinib-based Perioperative Adjuvant Therapy for A Case of Unresectable Stage IIIA(N2) Non-Small Cell Lung Cancer. AM J MED SCI, 2010; 340(4):321-5. (SCI,IF 1.257)

  14.Yan X, Zhu H, Wang H, Wang Q, Li P, Ma Z. The role of adjuvant chemotherapy in operable non-small cell lung cancer. Zhongguo Fei Ai Za Zhi. 2011;14(3):281-5. Chinese.

  15.Li P, Wang Q, Wang H, Ma Z. Research progresses of albumin-bound paclitaxel in the treatment of non-small cell lung cancer. Zhongguo Fei Ai Za Zhi. 2010;13(7):748-52. doi: 10.3779/j.issn.1009-3419.2010.07.16. Chinese.

  16.Song ZB, Gao SS, Yi XN, Li YJ, Wang QM, Zhuang ZH, Wang LD. Expression of MUC1 in esophageal squamous-cell carcinoma and its relationship with prognosis of patients from Linzhou city, a high incidence area of northern China. World J Gastroenterol. 2003 Mar;9(3):404-7.

  17.Ji Xue Li, L. D. Wang, Shu Zheng, Bin Liu, Ruifeng Guo, Qiming Wang, Zongmin Fan, Hong Chen, Zehao Zhuang, Jiye An, Chao Sun, Shegan Gao, Jilin Li, Zibo Song, Xinwei He, Yanjie Li, Shanshan Gao, Huaqin Guo, Dongling Xie, Xinna Yi, Zhonghua Ding and Chung S. Yang. Analysis on color endoscopic mass survey (iodine staining) and surgically resected esophageal specimen on the subjects at high-incidence area for esophageal cancer in Henan. Proc. Am. Assoc. Cancer Res, 2003, 44:

  18.Z B Song, S S Gao, X N Yi, Y J Li, Q M Wang, Z H Zhuang, L. D. Wang. Expression of MUC1 in esophageal squamous-cell carcinoma and its relationship with prognosis of patients from Linzhou city, a high incidence area of northernChina. World J Gastroenterol, 2003; 9(3):404-407

论文讲座

  1.Wang QM. Functional Polymorphisms in Cancer Stem Cell Marker Gene CD133 Predict Local Recurrence and Distant Metastasis in Non-Small Cell Lung Cancer Patients Treated With Definitive Radiotherapy. 2014 World Cancer Congress. Melbourne,Australia, 3 - 6 December 2014.

  2.Wang QM. Functional Polymorphisms in Cancer Stem Cell Marker Gene CD133 Predict Local Recurrence and Distant Metastasis in Non-Small Cell Lung Cancer Patients Treated With Definitive Radiotherapy. Journal of Thoracic Oncology (2014) 9 (Supplement 9): S7-S52. 10.1097/JTO.0000000000000131. 26-29 March 2014. The European Lung Cancer Conference 2014, Geneva,Switzerland.

  3.Wang QM. Functional Polymorphisms in Cancer Stem Cell Marker Gene CD133 Predict Local Recurrence and Distant Metastasis in Non-Small Cell Lung Cancer Patients Treated With Definitive Radiotherapy. May 2-4, 2014. The 11th international conference of the Asian Clinical Oncology Society, Taipei,Taiwan

  4.王启鸣,李鹏,Hongliang Liu,熊慧华,钱吉,Daniel Gomez,Zhensheng Liu,Li-E Wang Zhongxing Liao,Qingyi Wei. CD133的miRNA结合位点单核苷酸多态性可预测根治性放疗的非小细胞肺癌患者的局部复发和远处转移. 第八届中国肿瘤内科大会暨第三届中国肿瘤医师大会,2014.7.2-6, 北京

  5.Wang QM. SNP in CD133 Predict Recurrence and Metastasis in NSCLC With Radiotherapy. The 40th Annual Meeting of Korean Cancer Association (KCA), June 19-20, Seoul,Korea

  6.王启鸣. 肿瘤干细胞标志基因CD133的功能位点单核苷酸多态性可预测接受根治性放疗的非小细胞肺癌患者的局部复发和远处转移. 第十七届全国临床肿瘤学大会暨2014年CSCO学术年会, 2014,9.17-21,厦门

  7.王启鸣. Functional Polymorphisms in Cancer Stem Cell Marker Gene CD133 Predict Local Recurrence and Distant Metastasis in Non-Small Cell Lung Cancer Patients Treated With Definitive Radiotherapy. 中华医学会第八届全国肿瘤中青年学术会议.2014,11,13 -15,厦门. 优秀论文

  8.Wang QM. Functional Polymorphisms in Cancer Stem Cell Marker Gene CD133 Predict Local Recurrence and Distant Metastasis in Non-Small Cell Lung Cancer Patients Treated With Definitive Radiotherapy. 2013.10. Annual Meeting of 51st The Japan Society of Clinical Oncology (JSCO),Kyoto, Japan

  9.Wang QM. Polymorphisms in the microRNA binding-site in the stem cell marker gene CD133 modify susceptibility to and survival of gastric cancer. 2013.11. The 22nd Asia Pacific Cancer Conference (APCC), Tianjin,China

  10.Wang QM. Functional Polymorphisms in Cancer Stem Cell Marker Gene CD133 Predict Local Recurrence and Distant Metastasis in Non-Small Cell Lung Cancer Patients Treated With Definitive Radiotherapy. 中华医学会肿瘤学分会2013年学术年会. 北京. 大会宣读. 优秀论文奖

  11.Wang QM. Polymorphisms in the microRNA binding-site in the stem cell marker gene CD133 modify susceptibility to and survival of gastric cancer. 2013全国临床肿瘤学年会(CSCO),厦门, 大会宣读

  12.王启鸣. 肿瘤干细胞标志基因CD133的功能位点单核苷酸多态性可预测接受根治性放疗的非小细胞肺癌患者的局部复发和远处转移. 《第13届全国肺癌学术大会论文汇编》2013年,2013.09.9-10,长春

  13.Wang QM, Liu HL, Wang Li-E, Amos CI, Spitz MR, Wei QY. Functional polymorphisms in the stem-cell related pathway affect susceptibility to non-small cell lung cancer: a finding from Texas lung cancer genome-wide association study. 2012 AACR, Chicago,USA

科研项目

  1.2014年,河南省省级科研院所预研项目,肺癌干细胞标志基因的miRNA结合位点SNP对肺癌干细胞干性的调控作用,经费5万,项目负责人;

  2.2013年,优秀河南省卫生科技创新型人才工程,肺癌血清诊断、预后、预测microRNA的筛选,经费5万,项目负责人;

  3.2013年,留学人员科技活动项目择优资助经费项目,肺癌干细胞标志基因microRNA结合位点SNP的筛选与功能研究,经费3万,项目负责人;

  4.2012年,国家自然科学基金面上项目,肺癌干细胞标志基因microRNA结合位点SNP的筛选与功能研究,经费65万,项目负责人;

  5.2011年,河南省科技厅基础与前沿,肺癌血清诊断、预后、预测microRNA的筛选,经费5万,项目负责人;

  6.2011年,河南省卫生厅重点课题,肺癌血清microRNA指纹库的建立,经费5万,项目负责人;

  7.2010年,河南省卫生科技创新人才,经费4.5万,项目负责人;

  8.2010年,河南省医学重点学科临床专科学术带头人培养及高新技术引进项目,EGFR分子检测对非小细胞肺癌EGFR-TKIs靶向药物疗效预测和耐药逆转的作用,经费10.9万,项目负责人。

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